Description for Melanotan 2 MT2 10mg Peptide.

Melanotan 2 MT2 10mg Peptide – The Synthetic α-MSH Analog Driving Pigmentation and Neuroendocrine Research

What if a single cyclic peptide could flip a molecular switch in the brain and skin cells to trigger rapid, UV-independent tanning, profoundly influence sexual arousal pathways, suppress appetite in certain models, and serve as a precision tool for dissecting melanocortin receptor biology—all from a tiny 10mg vial? This is the captivating dual-world power of Melanotan 2 10mg Peptide (MT-II), a synthetic cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH) that has fascinated researchers for decades in dermatology, neuroendocrinology, sexual behavior, and metabolic signaling studies.

At Cali BioLab Peptides, Melanotan 2 10mg Peptide is supplied as a sterile, high-purity (≥99%) lyophilized powder in a 10mg research vial—third-party HPLC/MS verified, batch-specific COAs included, and shipped fast within the USA. Perfect for qualified investigators exploring MC1R-mediated melanogenesis, MC3R/MC4R-driven feeding and sexual behavior, or broader melanocortin pathway dynamics in controlled in-vitro, ex-vivo, or approved animal models.

Strict Disclaimer: For laboratory and scientific research use only. Not for human consumption, therapeutic, diagnostic, veterinary, or any non-research application. Strictly intended for qualified researchers conducting in-vitro, ex-vivo, or ethically approved animal model studies. Cali BioLab Peptides maintains full regulatory compliance.

Scientific Identifiers for Melanotan 2 10mg Peptide

• Full Chemical Name: Melanotan-II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂)
• CAS Number: 121062-08-6
• Molecular Formula: C₅₀H₆₉N₁₅O₉
• Molecular Weight: 1024.18 g/mol
• Sequence: Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH₂ (cyclic structure via Asp-Lys lactam bridge)
• PubChem CID: 92432
• Purity: ≥99% (HPLC and Mass Spectrometry verified)
• Appearance: White to off-white lyophilized powder

These identifiers confirm Melanotan 2 10mg Peptide as a potent, non-selective melanocortin receptor agonist with enhanced stability and CNS penetration.

What Is Melanotan 2 10mg Peptide and How Does It Work?

Melanotan 2 10mg Peptide (MT-II) is a cyclic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH), designed with strategic substitutions (Nle for Met, D-Phe for Phe, cyclization) to dramatically increase potency, stability, and receptor affinity at melanocortin receptors (MC1R–MC5R).

The "how" of Melanotan 2 10mg Peptide is multi-receptor:

• MC1R (skin melanocytes): Strongly activates eumelanin production → UV-independent tanning and photoprotection in models.
• MC3R/MC4R (CNS, hypothalamus): Modulates appetite suppression, sexual arousal (via dopamine pathways), and energy expenditure.
• MC4R (brain): Influences libido, erectile function, and reward circuitry in behavioral models.
• MC5R (various tissues): Minor roles in exocrine secretion.

The cyclic structure and D-amino acids extend half-life and allow excellent CNS penetration (intranasal or systemic routes effective), making Melanotan 2 10mg Peptide a versatile probe for melanocortin biology.

Here are professional examples of Melanotan 2 10mg Peptide research-grade lyophilized vials in sterile glass packaging:

Usage and Reconstitution Guidelines for Melanotan 2 10mg Peptide

Reconstitution is straightforward to preserve Melanotan 2 10mg Peptide bioactivity:

1. Allow vial to reach room temperature.
2. Add 1–2 mL bacteriostatic water or sterile PBS; gently swirl (avoid vigorous shaking).
3. Prepare stock solutions (e.g., 5 mg/mL) and dilute for working concentrations (typically 0.1–10 μg/kg in vivo or nM–μM in vitro).
4. Aliquot immediately and store at –80 °C; thawed aliquots stable 2–8 °C for days.

Common research routes: subcutaneous, intraperitoneal, or intranasal administration in animal models; direct addition to cell culture media.

Research Applications of Melanotan 2 10mg Peptide

Melanotan 2 10mg Peptide is applied across diverse fields:

• Melanogenesis and photoprotection studies (MC1R activation, eumelanin induction)
• Sexual behavior and libido research (MC4R-mediated arousal, erectile function models)
• Appetite regulation and energy homeostasis (MC3R/MC4R suppression of feeding)
• Neuroprotection and anti-inflammatory effects in brain injury models
• Pigmentation disorders analogs (vitiligo, erythropoietic protoporphyria proxies)
• Behavioral pharmacology (anxiety, reward, sexual motivation paradigms)

Key endpoints where Melanotan 2 10mg Peptide shines:

• Skin melanin content and UV protection (spectrophotometry, histology)
• Mating behavior and erectile responses in rodents/primates
• Food intake and body weight changes in metabolic models
• Neuronal survival and inflammation markers post-ischemia or trauma
• Receptor binding and cAMP assays in MC-expressing cell lines

Frequently Asked Questions About Melanotan 2 10mg Peptide

Q: How does Melanotan 2 10mg Peptide differ from Melanotan 1 (afamelanotide)? A: Melanotan 2 10mg Peptide is non-selective (activates MC1R–MC5R) with strong CNS effects (libido, appetite); Melanotan 1 is MC1R-selective, primarily for pigmentation without notable sexual or appetite effects.

Q: What dosing ranges are common in preclinical animal models? A: In-vivo studies often use 1–100 μg/kg (subcutaneous or intranasal); behavioral effects frequently appear at lower doses (1–10 μg/kg).

Q: Is Melanotan 2 10mg Peptide stable after reconstitution? A: Yes—stable for weeks refrigerated when aliquoted; freeze for longer storage.

Q: Can it be used in sexual behavior or libido models? A: Yes—preclinical data show robust pro-erectile and pro-sexual motivation effects via MC4R pathways.

Q: How to verify batch purity? A: Cross-reference the provided COA on the product page.

One Question That Could Shape Your Next Melanocortin Study

If you could selectively activate melanocortin pathways right now in your model system, would you prioritize pigmentation/photoprotection (MC1R), sexual arousal and libido (MC4R), appetite/energy balance (MC3R/MC4R), or a combination—and what specific endpoint would you measure first?

Your answer might just unlock your next key finding.

In summary, Melanotan 2 10mg Peptide from Cali BioLab Peptides is a potent, versatile melanocortin agonist for pigmentation, sexual behavior, metabolic, and neuroprotective research. With exceptional purity, reliable supply, and broad preclinical utility, it's ready to advance your 2026 investigations.

Order your Melanotan 2 10mg Peptide today at Cali BioLab Peptides and explore melanocortin receptor biology with precision and confidence.